liposomes
One of the biggest challenges in skin care is the delivery of active ingredients directly into the skin. It is known that the properties of a cosmetic result not only from the active ingredients it contains, but also from an efficient use of these substances. The more of an active ingredient penetrates the stratum corneum barrier in an appropriate concentration, the more efficient a cosmetic is. In recent years in cosmetology, modern technologies of active ingredient nano-encapsulation have been used more and more frequently in transporting active substances into the skin. Liposomes are most commonly used for this purpose.
What are liposomes?
Liposomes (“lipo” – fat, “soma” – body) are small water bubbles with a size of (0.01-1.0 microns) surrounded by a double lipid layer, the main task of which is to transport a variety of biologically active compounds.
Liposomes are formed spontaneously from phospholipids in an aqueous environment and are filled with a small amount of the aqueous solution from which they are formed. In association with the fact that the arrangement of phospholipids in liposomes is similar to the structure of a cell membrane, liposomes are able to penetrate deeper in the dermis. Thanks to this property it is possible to introduce active substances through subsequent layers of the epidermis.
These characteristics of liposomes make them ideal for the transport of sparingly soluble substances and the release of these substances in the desired location.
The liposomes used in cosmetic preparations play a dual role:
1 – they progressively release the active ingredients found in them;
2 – they penetrate the deeper layers of the skin.
The properties of the modern liposomal encapsulation technology have been used in the creation and development of Pharmann’s cosmeceutical technology. Thanks to this, the active substances contained in the products more effectively penetrate the stratum corneum of the dermis – as a result, the products are more effective and efficient.